BDBM50305124 7-(2-(dimethylamino)ethoxy)-2-(4-(3-phenylureido)phenyl)-9,10-dihydro-4H-benzo[d]pyrazolo[1,5-a][1,3]diazepine-3-carboxamide::CHEMBL592267

SMILES: CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(NC(=O)Nc2ccccc2)cc1

InChI Key: InChIKey=BHJYLPCXJRRFBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305124 (7-(2-(dimethylamino)ethoxy)-2-(4-(3-phenylureido)p...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C29H31N7O3/c1-35(2)16-17-39-23-12-13-24-20(18-23)14-15-36-28(33-24)25(27(30)37)26(34-36)19-8-10-22(11-9-19)32-29(38)31-21-6-4-3-5-7-21/h3-13,18,33H,14-17H2,1-2H3,(H2,30,37)(H2,31,32,38)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair