BDBM50305142 7-(2-hydroxyethoxy)-2-(4-phenoxyphenyl)-9,10-dihydro-4H-benzo[d]pyrazolo[1,5-a][1,3]diazepine-3-carboxamide::CHEMBL601096

SMILES: NC(=O)c1c2Nc3ccc(OCCO)cc3CCn2nc1-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=CJJCGLIJKQVIML-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305142   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305142 (7-(2-hydroxyethoxy)-2-(4-phenoxyphenyl)-9,10-dihyd...) Show SMILES NC(=O)c1c2Nc3ccc(OCCO)cc3CCn2nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H24N4O4/c27-25(32)23-24(17-6-8-20(9-7-17)34-19-4-2-1-3-5-19)29-30-13-12-18-16-21(33-15-14-31)10-11-22(18)28-26(23)30/h1-11,16,28,31H,12-15H2,(H2,27,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair