BDBM50305144 2-(4-phenoxyphenyl)-7-(pyridin-2-ylmethoxy)-9,10-dihydro-4H-benzo[d]pyrazolo[1,5-a][1,3]diazepine-3-carboxamide::CHEMBL591091

SMILES: NC(=O)c1c2Nc3ccc(OCc4ccccn4)cc3CCn2nc1-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=XTRKHZOUCWZBMT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305144 (2-(4-phenoxyphenyl)-7-(pyridin-2-ylmethoxy)-9,10-d...) Show SMILES NC(=O)c1c2Nc3ccc(OCc4ccccn4)cc3CCn2nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C30H25N5O3/c31-29(36)27-28(20-9-11-24(12-10-20)38-23-7-2-1-3-8-23)34-35-17-15-21-18-25(13-14-26(21)33-30(27)35)37-19-22-6-4-5-16-32-22/h1-14,16,18,33H,15,17,19H2,(H2,31,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair