BDBM50305350 (+/-)-2-(2-aminoethoxy)-3-(1-o-tolyl-1H-imidazol-4-yl)propanoic acid::CHEMBL606237

SMILES: Cc1ccccc1-n1cnc(CC(OCCN)C(O)=O)c1

InChI Key: InChIKey=WUAXKGSLSYPFBN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxypeptidase B2 isoform A (Homo sapiens (Human))	BDBM50305350 ((+/-)-2-(2-aminoethoxy)-3-(1-o-tolyl-1H-imidazol-4...) Show SMILES Cc1ccccc1-n1cnc(CC(OCCN)C(O)=O)c1 Show InChI InChI=1S/C15H19N3O3/c1-11-4-2-3-5-13(11)18-9-12(17-10-18)8-14(15(19)20)21-7-6-16/h2-5,9-10,14H,6-8,16H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Thrombin-activatable fibrinolysis (TAFI) (Homo sapiens (Human))	BDBM50305350 ((+/-)-2-(2-aminoethoxy)-3-(1-o-tolyl-1H-imidazol-4...) Show SMILES Cc1ccccc1-n1cnc(CC(OCCN)C(O)=O)c1 Show InChI InChI=1S/C15H19N3O3/c1-11-4-2-3-5-13(11)18-9-12(17-10-18)8-14(15(19)20)21-7-6-16/h2-5,9-10,14H,6-8,16H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair