BDBM50305367 CHEMBL590618::N-((6-chloropyridin-3-yl)methyl)-N-methyl-1-(6-phenylpyridazin-3-yl)pyrrolidin-3-amine

SMILES: CN(Cc1ccc(Cl)nc1)C1CCN(C1)c1ccc(nn1)-c1ccccc1

InChI Key: InChIKey=PRVRMYHQBZFUEW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50305367 (CHEMBL590618 | N-((6-chloropyridin-3-yl)methyl)-N-...) Show SMILES CN(Cc1ccc(Cl)nc1)C1CCN(C1)c1ccc(nn1)-c1ccccc1 Show InChI InChI=1S/C21H22ClN5/c1-26(14-16-7-9-20(22)23-13-16)18-11-12-27(15-18)21-10-8-19(24-25-21)17-5-3-2-4-6-17/h2-10,13,18H,11-12,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]585539 from alpha7 nAChR in rat brain				Bioorg Med Chem Lett 20: 104-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.023 BindingDB Entry DOI: 10.7270/Q2RF5VZQ
					More data for this Ligand-Target Pair