BDBM50305388 2-(3-(4-benzyl-4-hydroxypiperidine-1-carbonyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazol-4-yl)acetonitrile::CHEMBL592051

SMILES: OC1(Cc2ccccc2)CCN(CC1)C(=O)c1nn(c(c1CC#N)-c1ccc(Cl)cc1)-c1ccccc1Cl

InChI Key: InChIKey=BPRPWFMPSMOCSC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50305388 (2-(3-(4-benzyl-4-hydroxypiperidine-1-carbonyl)-1-(...) Show SMILES OC1(Cc2ccccc2)CCN(CC1)C(=O)c1nn(c(c1CC#N)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C30H26Cl2N4O2/c31-23-12-10-22(11-13-23)28-24(14-17-33)27(34-36(28)26-9-5-4-8-25(26)32)29(37)35-18-15-30(38,16-19-35)20-21-6-2-1-3-7-21/h1-13,38H,14-16,18-20H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS binding				Bioorg Med Chem Lett 20: 26-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.047 BindingDB Entry DOI: 10.7270/Q28G8KS9
					More data for this Ligand-Target Pair