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BDBM50305406 1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(2-(piperidin-1-yl)ethyl)-1H-pyrazole-3-carboxamide::CHEMBL589159

SMILES: Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)NCCN1CCCCC1

InChI Key: InChIKey=KHAAKYNGKAYXSE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305406   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50305406
PNG
(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...)
Show SMILES Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)NCCN1CCCCC1
Show InChI InChI=1S/C25H25Cl2N5O/c26-19-10-8-18(9-11-19)24-20(12-13-28)23(30-32(24)22-7-3-2-6-21(22)27)25(33)29-14-17-31-15-4-1-5-16-31/h2-3,6-11H,1,4-5,12,14-17H2,(H,29,33)
PDB

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KEGG

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.11E+3n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS binding


Bioorg Med Chem Lett 20: 26-30 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.047
BindingDB Entry DOI: 10.7270/Q28G8KS9
More data for this
Ligand-Target Pair