BDBM50305409 1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(6-(trifluoromethyl)pyridin-3-yl)-1H-pyrazole-3-carboxamide::CHEMBL592281

SMILES: FC(F)(F)c1ccc(NC(=O)c2nn(c(c2CC#N)-c2ccc(Cl)cc2)-c2ccccc2Cl)cn1

InChI Key: InChIKey=SKZVTNBNJGVZRH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50305409 (1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...) Show SMILES FC(F)(F)c1ccc(NC(=O)c2nn(c(c2CC#N)-c2ccc(Cl)cc2)-c2ccccc2Cl)cn1 Show InChI InChI=1S/C24H14Cl2F3N5O/c25-15-7-5-14(6-8-15)22-17(11-12-30)21(33-34(22)19-4-2-1-3-18(19)26)23(35)32-16-9-10-20(31-13-16)24(27,28)29/h1-10,13H,11H2,(H,32,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS binding				Bioorg Med Chem Lett 20: 26-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.047 BindingDB Entry DOI: 10.7270/Q28G8KS9
					More data for this Ligand-Target Pair