BDBM50305411 1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(quinolin-3-yl)-1H-pyrazole-3-carboxamide::CHEMBL589157

SMILES: Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)Nc1cnc2ccccc2c1

InChI Key: InChIKey=UPGMTVZTKSVXPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50305411 (1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...) Show SMILES Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C27H17Cl2N5O/c28-19-11-9-17(10-12-19)26-21(13-14-30)25(33-34(26)24-8-4-2-6-22(24)29)27(35)32-20-15-18-5-1-3-7-23(18)31-16-20/h1-12,15-16H,13H2,(H,32,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS binding				Bioorg Med Chem Lett 20: 26-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.047 BindingDB Entry DOI: 10.7270/Q28G8KS9
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