BDBM50305436 2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(2-(4-fluorophenyl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile::CHEMBL589400

SMILES: Fc1ccc(cc1)C1CCCCN1C(=O)c1nn(c(c1CC#N)-c1ccc(Cl)cc1)-c1ccccc1Cl

InChI Key: InChIKey=DOTRNDAQICTKOW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50305436 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(2-(4-f...) Show SMILES Fc1ccc(cc1)C1CCCCN1C(=O)c1nn(c(c1CC#N)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C29H23Cl2FN4O/c30-21-12-8-20(9-13-21)28-23(16-17-33)27(34-36(28)26-7-2-1-5-24(26)31)29(37)35-18-4-3-6-25(35)19-10-14-22(32)15-11-19/h1-2,5,7-15,25H,3-4,6,16,18H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS binding				Bioorg Med Chem Lett 20: 26-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.047 BindingDB Entry DOI: 10.7270/Q28G8KS9
					More data for this Ligand-Target Pair