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SMILES: FC(F)(F)c1ccc2CCN(Cc2c1)C(=O)c1nn(c(c1CC#N)-c1ccc(Cl)cc1)-c1ccccc1Cl

InChI Key: InChIKey=OAQQRLGMKZEVFV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305438   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))		BDBM50305438
PNG
(2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(7-(tri...)
Show SMILES FC(F)(F)c1ccc2CCN(Cc2c1)C(=O)c1nn(c(c1CC#N)-c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C28H19Cl2F3N4O/c29-21-9-6-18(7-10-21)26-22(11-13-34)25(35-37(26)24-4-2-1-3-23(24)30)27(38)36-14-12-17-5-8-20(28(31,32)33)15-19(17)16-36/h1-10,15H,11-12,14,16H2
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Similars
Article
PubMed
n/an/a 2.10n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS binding

Bioorg Med Chem Lett 20: 26-30 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.047
BindingDB Entry DOI: 10.7270/Q28G8KS9
More data for this
Ligand-Target Pair