null

SMILES: COCCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1

InChI Key: InChIKey=JDPUXQSKWRFVOE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50305567 (CHEMBL589863 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...) Show SMILES COCCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 Show InChI InChI=1S/C13H16BrN3O4S3/c1-8-6-11(22-9(8)4-3-5-21-2)24(19,20)17-12(18)16-13-15-7-10(14)23-13/h6-7H,3-5H2,1-2H3,(H2,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inhibition of FBPase in human liver				Bioorg Med Chem Lett 20: 594-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.093 BindingDB Entry DOI: 10.7270/Q27H1JPX
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Mus musculus)	BDBM50305567 (CHEMBL589863 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...) Show SMILES COCCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 Show InChI InChI=1S/C13H16BrN3O4S3/c1-8-6-11(22-9(8)4-3-5-21-2)24(19,20)17-12(18)16-13-15-7-10(14)23-13/h6-7H,3-5H2,1-2H3,(H2,15,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inhibition of FBPase in mouse liver				Bioorg Med Chem Lett 20: 594-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.093 BindingDB Entry DOI: 10.7270/Q27H1JPX
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50305567 (CHEMBL589863 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...) Show SMILES COCCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 Show InChI InChI=1S/C13H16BrN3O4S3/c1-8-6-11(22-9(8)4-3-5-21-2)24(19,20)17-12(18)16-13-15-7-10(14)23-13/h6-7H,3-5H2,1-2H3,(H2,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrate				Bioorg Med Chem Lett 20: 594-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.093 BindingDB Entry DOI: 10.7270/Q27H1JPX
					More data for this Ligand-Target Pair