BDBM50305699 1-(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-3-methylphenyl)ethane-1,2-diol hydrochloride::CHEMBL594601

SMILES: Cc1cc(ccc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12)C(O)CO

InChI Key: InChIKey=NPIPKTZIQRILBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50305699 (1-(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4...) Show SMILES Cc1cc(ccc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12)C(O)CO Show InChI InChI=1S/C21H17F2N3O2S/c1-12-8-13(18(28)11-27)2-5-16(12)21-25-24-20-7-4-15(10-26(20)21)29-19-6-3-14(22)9-17(19)23/h2-10,18,27-28H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38 alpha				Bioorg Med Chem Lett 20: 469-73 (2010) Article DOI: 10.1016/j.bmcl.2009.11.114 BindingDB Entry DOI: 10.7270/Q2G160XP
					More data for this Ligand-Target Pair