BDBM50305709 3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-N-(2-hydroxyethyl)-4-methylbenzamide hydrochloride::CHEMBL607089

SMILES: Cc1ccc(cc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12)C(=O)NCCO

InChI Key: InChIKey=OVCGPEVTYSGZAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50305709 (3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...) Show SMILES Cc1ccc(cc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12)C(=O)NCCO Show InChI InChI=1S/C22H18F2N4O2S/c1-13-2-3-14(22(30)25-8-9-29)10-17(13)21-27-26-20-7-5-16(12-28(20)21)31-19-6-4-15(23)11-18(19)24/h2-7,10-12,29H,8-9H2,1H3,(H,25,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38 alpha				Bioorg Med Chem Lett 20: 469-73 (2010) Article DOI: 10.1016/j.bmcl.2009.11.114 BindingDB Entry DOI: 10.7270/Q2G160XP
					More data for this Ligand-Target Pair