BindingDB logo
myBDB logout

null

SMILES: CN1CCN(CC1)c1cnc(NC(=O)[C@H](c2ccc(Cl)cc2)C(C)(C)C)s1

InChI Key: InChIKey=PVWZESZRODUNDT-KRWDZBQOSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305915   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))		BDBM50305915
PNG
((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(4-methyl...)
Show SMILES CN1CCN(CC1)c1cnc(NC(=O)[C@H](c2ccc(Cl)cc2)C(C)(C)C)s1 |r|
Show InChI InChI=1S/C20H27ClN4OS/c1-20(2,3)17(14-5-7-15(21)8-6-14)18(26)23-19-22-13-16(27-19)25-11-9-24(4)10-12-25/h5-8,13,17H,9-12H2,1-4H3,(H,22,23,26)/t17-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production

Bioorg Med Chem Lett 20: 493-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.112
BindingDB Entry DOI: 10.7270/Q21V5F2Q
More data for this
Ligand-Target Pair