BDBM50305930 1-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)cyclobutanecarboxamide::CHEMBL609291

SMILES: Fc1cnc(NC(=O)C2(CCC2)c2ccc(Cl)cc2)s1

InChI Key: InChIKey=PWSJXJFWBIEKCU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305930 (1-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)cyclobu...) Show SMILES Fc1cnc(NC(=O)C2(CCC2)c2ccc(Cl)cc2)s1 Show InChI InChI=1S/C14H12ClFN2OS/c15-10-4-2-9(3-5-10)14(6-1-7-14)12(19)18-13-17-8-11(16)20-13/h2-5,8H,1,6-7H2,(H,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair