null

SMILES: Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2ccccc2)cnc1C#CC(C)(C)O

InChI Key: InChIKey=SLOGHVOSBVGLSQ-NRFANRHFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50306099 ((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2ccccc2)cnc1C#CC(C)(C)O |r| Show InChI InChI=1S/C27H28N4O2/c1-18-23-14-20(9-10-26(23)31-30-18)24-15-22(16-29-25(24)11-12-27(2,3)32)33-17-21(28)13-19-7-5-4-6-8-19/h4-10,14-16,21,32H,13,17,28H2,1-3H3,(H,30,31)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of truncated AKT1				Bioorg Med Chem Lett 20: 673-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.064 BindingDB Entry DOI: 10.7270/Q2D21XQ0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50306099 ((S)-4-(5-(2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2ccccc2)cnc1C#CC(C)(C)O |r| Show InChI InChI=1S/C27H28N4O2/c1-18-23-14-20(9-10-26(23)31-30-18)24-15-22(16-29-25(24)11-12-27(2,3)32)33-17-21(28)13-19-7-5-4-6-8-19/h4-10,14-16,21,32H,13,17,28H2,1-3H3,(H,30,31)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of ROCK1				Bioorg Med Chem Lett 20: 673-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.064 BindingDB Entry DOI: 10.7270/Q2D21XQ0
					More data for this Ligand-Target Pair