BDBM50306139 6-chloro-N-((3S)-1-(2-fluoro-4-(1-(isopropyl(methyl)amino)ethyl)phenyl)-2-oxopyrrolidin-3-yl)naphthalene-2-sulfonamide::CHEMBL594538

SMILES: CC(C)N(C)C(C)c1ccc(N2CC[C@H](NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)c(F)c1

InChI Key: InChIKey=INOOWBQEHMZJJL-UCSBTNPJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50306139 (6-chloro-N-((3S)-1-(2-fluoro-4-(1-(isopropyl(methy...) Show SMILES CC(C)N(C)C(C)c1ccc(N2CC[C@H](NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)c(F)c1 |r| Show InChI InChI=1S/C26H29ClFN3O3S/c1-16(2)30(4)17(3)18-7-10-25(23(28)15-18)31-12-11-24(26(31)32)29-35(33,34)22-9-6-19-13-21(27)8-5-20(19)14-22/h5-10,13-17,24,29H,11-12H2,1-4H3/t17?,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human factor 10a by fluorescence assay				Bioorg Med Chem Lett 20: 618-22 (2010) Article DOI: 10.1016/j.bmcl.2009.11.077 BindingDB Entry DOI: 10.7270/Q24M94NN
					More data for this Ligand-Target Pair