BDBM50306151 (S)-N-(1-(4-acetyl-2-fluorophenyl)-2-oxopyrrolidin-3-yl)-2-(5-chlorothiophen-2-yl)ethenesulfonamide::CHEMBL594311
SMILES: CC(=O)c1ccc(N2CC[C@H](NS(=O)(=O)C=Cc3ccc(Cl)s3)C2=O)c(F)c1
InChI Key: InChIKey=DNSKKBFCDBILLO-HNNXBMFYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50306151 ((S)-N-(1-(4-acetyl-2-fluorophenyl)-2-oxopyrrolidin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human factor 10a by fluorescence assay | Bioorg Med Chem Lett 20: 618-22 (2010) Article DOI: 10.1016/j.bmcl.2009.11.077 BindingDB Entry DOI: 10.7270/Q24M94NN | |||||||||||
More data for this Ligand-Target Pair |