BDBM50306185 2-(3-hydroxy-4-((methylamino)methyl)phenyl)-2H-indazole-7-carboxamide::CHEMBL596582

SMILES: CNCc1ccc(cc1O)-n1cc2cccc(C(N)=O)c2n1

InChI Key: InChIKey=ZQZSVSDOTRUFQP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50306185 (2-(3-hydroxy-4-((methylamino)methyl)phenyl)-2H-ind...) Show SMILES CNCc1ccc(cc1O)-n1cc2cccc(C(N)=O)c2n1 Show InChI InChI=1S/C16H16N4O2/c1-18-8-10-5-6-12(7-14(10)21)20-9-11-3-2-4-13(16(17)22)15(11)19-20/h2-7,9,18,21H,8H2,1H3,(H2,17,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assay				Bioorg Med Chem Lett 20: 488-92 (2010) Article DOI: 10.1016/j.bmcl.2009.11.127 BindingDB Entry DOI: 10.7270/Q2W37WFZ
					More data for this Ligand-Target Pair