BDBM50306238 1-(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazole-3-carbonyl)-4-(5-fluoropyridin-2-yl)piperidine-4-carboxylic acid::CHEMBL594159

SMILES: NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)(C(O)=O)c1ccc(F)cn1

InChI Key: InChIKey=SKHJYMXKKBQLIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306238 (1-(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)(C(O)=O)c1ccc(F)cn1 Show InChI InChI=1S/C29H24Cl2FN5O4/c30-18-7-5-17(6-8-18)26-20(15-24(33)38)25(35-37(26)22-4-2-1-3-21(22)31)27(39)36-13-11-29(12-14-36,28(40)41)23-10-9-19(32)16-34-23/h1-10,16H,11-15H2,(H2,33,38)(H,40,41)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair