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SMILES: COc1ccc2occ(CCN3CCC(=CC3)c3c[nH]c4ccccc34)c2c1

InChI Key: InChIKey=RXVKGDHVYOJJTH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306463   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50306463
PNG
(3-(1-(2-(5-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Show SMILES COc1ccc2occ(CCN3CCC(=CC3)c3c[nH]c4ccccc34)c2c1 |c:14|
Show InChI InChI=1S/C24H24N2O2/c1-27-19-6-7-24-21(14-19)18(16-28-24)10-13-26-11-8-17(9-12-26)22-15-25-23-5-3-2-4-20(22)23/h2-8,14-16,25H,9-13H2,1H3
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 11n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomes

Bioorg Med Chem Lett 20: 824-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.093
BindingDB Entry DOI: 10.7270/Q2B56JVJ
More data for this
Ligand-Target Pair