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BDBM50306466 7-ethyl-3-(1-(2-(5-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole::CHEMBL597434

SMILES: CCc1cccc2c(c[nH]c12)C1=CCN(CCc2coc3ccc(OC)cc23)CC1

InChI Key: InChIKey=NCOVTDFDEMEMLS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306466   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine transporters; Norepinephrine & serotonin


(Rattus norvegicus (rat))
BDBM50306466
PNG
(7-ethyl-3-(1-(2-(5-methoxybenzofuran-3-yl)ethyl)-1...)
Show SMILES CCc1cccc2c(c[nH]c12)C1=CCN(CCc2coc3ccc(OC)cc23)CC1 |t:13|
Show InChI InChI=1S/C26H28N2O2/c1-3-18-5-4-6-22-24(16-27-26(18)22)19-9-12-28(13-10-19)14-11-20-17-30-25-8-7-21(29-2)15-23(20)25/h4-9,15-17,27H,3,10-14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
41n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomes


Bioorg Med Chem Lett 20: 824-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.093
BindingDB Entry DOI: 10.7270/Q2B56JVJ
More data for this
Ligand-Target Pair