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SMILES: COc1cccc2c(coc12)C(C)CN1CCC(=CC1)c1c[nH]c2cc(F)ccc12

InChI Key: InChIKey=RJJULGLATNVXBG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306477   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50306477
PNG
(6-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)propyl)...)
Show SMILES COc1cccc2c(coc12)C(C)CN1CCC(=CC1)c1c[nH]c2cc(F)ccc12 |c:19|
Show InChI InChI=1S/C25H25FN2O2/c1-16(22-15-30-25-20(22)4-3-5-24(25)29-2)14-28-10-8-17(9-11-28)21-13-27-23-12-18(26)6-7-19(21)23/h3-8,12-13,15-16,27H,9-11,14H2,1-2H3
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.97n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomes

Bioorg Med Chem Lett 20: 824-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.093
BindingDB Entry DOI: 10.7270/Q2B56JVJ
More data for this
Ligand-Target Pair