BDBM50306493 2-(5-((2R,5S)-4-benzhydryl-2,5-dimethylpiperazine-1-carbonyl)-6-chloro-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide::CHEMBL591217

SMILES: C[C@H]1CN([C@H](C)CN1C(c1ccccc1)c1ccccc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C

InChI Key: InChIKey=HIAKXKGKRDVPMY-FCHUYYIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306493 (2-(5-((2R,5S)-4-benzhydryl-2,5-dimethylpiperazine-...) Show SMILES C[C@H]1CN([C@H](C)CN1C(c1ccccc1)c1ccccc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C |r| Show InChI InChI=1S/C33H35ClN4O3/c1-21-19-38(22(2)18-37(21)30(23-12-8-6-9-13-23)24-14-10-7-11-15-24)32(40)26-16-25-27(31(39)33(41)35(3)4)20-36(5)29(25)17-28(26)34/h6-17,20-22,30H,18-19H2,1-5H3/t21-,22+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair