BDBM50306511 4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid::CHEMBL590984

SMILES: CCCc1c(SC)c2ccc(NC(=O)C(CC)c3ccccc3)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=ZMGXUFQMCWERPK-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50306511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50306511 (4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...) Show SMILES CCCc1c(SC)c2ccc(NC(=O)C(CC)c3ccccc3)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C36H36N2O3S/c1-4-11-32-34(42-3)31-21-20-27(37-35(39)28(5-2)25-12-7-6-8-13-25)22-33(31)38(32)23-24-16-18-26(19-17-24)29-14-9-10-15-30(29)36(40)41/h6-10,12-22,28H,4-5,11,23H2,1-3H3,(H,37,39)(H,40,41)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Displacement of radiolabled GW2433 from human PPARalpha ligand binding domain expressed in Escherichia coli				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50306511 (4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...) Show SMILES CCCc1c(SC)c2ccc(NC(=O)C(CC)c3ccccc3)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C36H36N2O3S/c1-4-11-32-34(42-3)31-21-20-27(37-35(39)28(5-2)25-12-7-6-8-13-25)22-33(31)38(32)23-24-16-18-26(19-17-24)29-14-9-10-15-30(29)36(40)41/h6-10,12-22,28H,4-5,11,23H2,1-3H3,(H,37,39)(H,40,41)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assay				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50306511 (4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...) Show SMILES CCCc1c(SC)c2ccc(NC(=O)C(CC)c3ccccc3)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C36H36N2O3S/c1-4-11-32-34(42-3)31-21-20-27(37-35(39)28(5-2)25-12-7-6-8-13-25)22-33(31)38(32)23-24-16-18-26(19-17-24)29-14-9-10-15-30(29)36(40)41/h6-10,12-22,28H,4-5,11,23H2,1-3H3,(H,37,39)(H,40,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	201	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assay				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50306511 (4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...) Show SMILES CCCc1c(SC)c2ccc(NC(=O)C(CC)c3ccccc3)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C36H36N2O3S/c1-4-11-32-34(42-3)31-21-20-27(37-35(39)28(5-2)25-12-7-6-8-13-25)22-33(31)38(32)23-24-16-18-26(19-17-24)29-14-9-10-15-30(29)36(40)41/h6-10,12-22,28H,4-5,11,23H2,1-3H3,(H,37,39)(H,40,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Displacement of radiolabled ((5-{4-[Methyl-pyridin-2yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione) from human PPARgamma ligand binding domain expr...				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50306511 (4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...) Show SMILES CCCc1c(SC)c2ccc(NC(=O)C(CC)c3ccccc3)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C36H36N2O3S/c1-4-11-32-34(42-3)31-21-20-27(37-35(39)28(5-2)25-12-7-6-8-13-25)22-33(31)38(32)23-24-16-18-26(19-17-24)29-14-9-10-15-30(29)36(40)41/h6-10,12-22,28H,4-5,11,23H2,1-3H3,(H,37,39)(H,40,41)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Displacement of radiolabled GW2433 from human PPARdelta ligand binding domain expressed in Escherichia coli				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair