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BDBM50306518 4'-((6-(1-phenylpropylcarbamoyl)-2-propyl-1H-benzo[d]imidazol-1-yl)methyl)biphenyl-2-carboxylic acid::CHEMBL601678

SMILES: CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NC(CC)c1ccccc1

InChI Key: InChIKey=JNILOFBNNHPODI-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50306518   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor delta


(Mus musculus)
BDBM50306518
PNG
(4'-((6-(1-phenylpropylcarbamoyl)-2-propyl-1H-benzo...)
Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NC(CC)c1ccccc1
Show InChI InChI=1S/C34H33N3O3/c1-3-10-32-35-30-20-19-26(33(38)36-29(4-2)25-11-6-5-7-12-25)21-31(30)37(32)22-23-15-17-24(18-16-23)27-13-8-9-14-28(27)34(39)40/h5-9,11-21,29H,3-4,10,22H2,1-2H3,(H,36,38)(H,39,40)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Agonist activity at mouse PPARdelta expressed in african green monkey CV1 cells by Gal4 transactivation assay


Bioorg Med Chem Lett 20: 1399-404 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.107
BindingDB Entry DOI: 10.7270/Q2T43T5R
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Mus musculus)
BDBM50306518
PNG
(4'-((6-(1-phenylpropylcarbamoyl)-2-propyl-1H-benzo...)
Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NC(CC)c1ccccc1
Show InChI InChI=1S/C34H33N3O3/c1-3-10-32-35-30-20-19-26(33(38)36-29(4-2)25-11-6-5-7-12-25)21-31(30)37(32)22-23-15-17-24(18-16-23)27-13-8-9-14-28(27)34(39)40/h5-9,11-21,29H,3-4,10,22H2,1-2H3,(H,36,38)(H,39,40)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Agonist activity at mouse PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assay


Bioorg Med Chem Lett 20: 1399-404 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.107
BindingDB Entry DOI: 10.7270/Q2T43T5R
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50306518
PNG
(4'-((6-(1-phenylpropylcarbamoyl)-2-propyl-1H-benzo...)
Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NC(CC)c1ccccc1
Show InChI InChI=1S/C34H33N3O3/c1-3-10-32-35-30-20-19-26(33(38)36-29(4-2)25-11-6-5-7-12-25)21-31(30)37(32)22-23-15-17-24(18-16-23)27-13-8-9-14-28(27)34(39)40/h5-9,11-21,29H,3-4,10,22H2,1-2H3,(H,36,38)(H,39,40)
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n/an/an/an/a 900n/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assay


Bioorg Med Chem Lett 20: 1399-404 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.107
BindingDB Entry DOI: 10.7270/Q2T43T5R
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50306518
PNG
(4'-((6-(1-phenylpropylcarbamoyl)-2-propyl-1H-benzo...)
Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NC(CC)c1ccccc1
Show InChI InChI=1S/C34H33N3O3/c1-3-10-32-35-30-20-19-26(33(38)36-29(4-2)25-11-6-5-7-12-25)21-31(30)37(32)22-23-15-17-24(18-16-23)27-13-8-9-14-28(27)34(39)40/h5-9,11-21,29H,3-4,10,22H2,1-2H3,(H,36,38)(H,39,40)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assay


Bioorg Med Chem Lett 20: 1399-404 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.107
BindingDB Entry DOI: 10.7270/Q2T43T5R
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Mus musculus)
BDBM50306518
PNG
(4'-((6-(1-phenylpropylcarbamoyl)-2-propyl-1H-benzo...)
Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NC(CC)c1ccccc1
Show InChI InChI=1S/C34H33N3O3/c1-3-10-32-35-30-20-19-26(33(38)36-29(4-2)25-11-6-5-7-12-25)21-31(30)37(32)22-23-15-17-24(18-16-23)27-13-8-9-14-28(27)34(39)40/h5-9,11-21,29H,3-4,10,22H2,1-2H3,(H,36,38)(H,39,40)
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n/an/an/an/a 1.69E+3n/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Agonist activity at mouse PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assay


Bioorg Med Chem Lett 20: 1399-404 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.107
BindingDB Entry DOI: 10.7270/Q2T43T5R
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50306518
PNG
(4'-((6-(1-phenylpropylcarbamoyl)-2-propyl-1H-benzo...)
Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NC(CC)c1ccccc1
Show InChI InChI=1S/C34H33N3O3/c1-3-10-32-35-30-20-19-26(33(38)36-29(4-2)25-11-6-5-7-12-25)21-31(30)37(32)22-23-15-17-24(18-16-23)27-13-8-9-14-28(27)34(39)40/h5-9,11-21,29H,3-4,10,22H2,1-2H3,(H,36,38)(H,39,40)
PDB

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antibodypedia
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PC sid
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n/an/an/an/a>1.00E+4n/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells by Gal4 transactivation assay


Bioorg Med Chem Lett 20: 1399-404 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.107
BindingDB Entry DOI: 10.7270/Q2T43T5R
More data for this
Ligand-Target Pair