null

SMILES: CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCN(CC3)C(=O)OC(C)(C)C)c2n1

InChI Key: InChIKey=CEPZLSYRIXXARR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50306621 (CHEMBL600084 | tert-butyl 4-(4-(8-oxa-3-azabicyclo...) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCN(CC3)C(=O)OC(C)(C)C)c2n1 Show InChI InChI=1S/C29H38N8O4/c1-29(2,3)41-28(39)35-13-11-20(12-14-35)37-26-23(15-31-37)25(36-16-21-9-10-22(17-36)40-21)33-24(34-26)18-5-7-19(8-6-18)32-27(38)30-4/h5-8,15,20-22H,9-14,16-17H2,1-4H3,(H2,30,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha				Bioorg Med Chem Lett 20: 1440-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.086 BindingDB Entry DOI: 10.7270/Q2S46S2T
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50306621 (CHEMBL600084 | tert-butyl 4-(4-(8-oxa-3-azabicyclo...) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCN(CC3)C(=O)OC(C)(C)C)c2n1 Show InChI InChI=1S/C29H38N8O4/c1-29(2,3)41-28(39)35-13-11-20(12-14-35)37-26-23(15-31-37)25(36-16-21-9-10-22(17-36)40-21)33-24(34-26)18-5-7-19(8-6-18)32-27(38)30-4/h5-8,15,20-22H,9-14,16-17H2,1-4H3,(H2,30,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of mTOR				Bioorg Med Chem Lett 20: 1440-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.086 BindingDB Entry DOI: 10.7270/Q2S46S2T
					More data for this Ligand-Target Pair