BDBM50306678 CHEMBL591457::rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)propanamide

SMILES: CC(Oc1ccc2ncc(CCC(N)=O)cc2c1)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=SFRHDNQDYJKYRK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50306678 (CHEMBL591457 | rac-3-(6-(1-(2,6-dichloro-3-fluorop...) Show SMILES CC(Oc1ccc2ncc(CCC(N)=O)cc2c1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C20H17Cl2FN2O2/c1-11(19-15(21)4-5-16(23)20(19)22)27-14-3-6-17-13(9-14)8-12(10-25-17)2-7-18(24)26/h3-6,8-11H,2,7H2,1H3,(H2,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co, Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant KDR by TR-FRET assay				Bioorg Med Chem Lett 20: 1405-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.109 BindingDB Entry DOI: 10.7270/Q2HQ401G
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50306678 (CHEMBL591457 | rac-3-(6-(1-(2,6-dichloro-3-fluorop...) Show SMILES CC(Oc1ccc2ncc(CCC(N)=O)cc2c1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C20H17Cl2FN2O2/c1-11(19-15(21)4-5-16(23)20(19)22)27-14-3-6-17-13(9-14)8-12(10-25-17)2-7-18(24)26/h3-6,8-11H,2,7H2,1H3,(H2,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co, Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant Src by TR-FRET assay				Bioorg Med Chem Lett 20: 1405-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.109 BindingDB Entry DOI: 10.7270/Q2HQ401G
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50306678 (CHEMBL591457 | rac-3-(6-(1-(2,6-dichloro-3-fluorop...) Show SMILES CC(Oc1ccc2ncc(CCC(N)=O)cc2c1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C20H17Cl2FN2O2/c1-11(19-15(21)4-5-16(23)20(19)22)27-14-3-6-17-13(9-14)8-12(10-25-17)2-7-18(24)26/h3-6,8-11H,2,7H2,1H3,(H2,24,26)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co, Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met by TR-FRET assay				Bioorg Med Chem Lett 20: 1405-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.109 BindingDB Entry DOI: 10.7270/Q2HQ401G
					More data for this Ligand-Target Pair