BDBM50306878 8-Methoxy-6-methyl-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[1,2,3-cd]indol-5-one::CHEMBL599313

SMILES: COc1cccc2c1cc1N(C)C(=O)c3cc4OCOc4c2c13

InChI Key: InChIKey=PXEFALHTNGHZOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50306878 (8-Methoxy-6-methyl-6H-benzo[f][1,3]dioxolo[4',5':4...) Show SMILES COc1cccc2c1cc1N(C)C(=O)c3cc4OCOc4c2c13 Show InChI InChI=1S/C18H13NO4/c1-19-12-6-10-9(4-3-5-13(10)21-2)16-15(12)11(18(19)20)7-14-17(16)23-8-22-14/h3-7H,8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 20: 1384-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.007 BindingDB Entry DOI: 10.7270/Q2QF8TTB
					More data for this Ligand-Target Pair