BDBM50307371 (+/-)-2-(4'-Ethoxyphenyl)thiomorpholin-5-one::CHEMBL597769

SMILES: CCOc1ccc(cc1)C1CNC(=O)CS1

InChI Key: InChIKey=CBRYZPDPVZGCMA-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50307371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50307371 ((+/-)-2-(4'-Ethoxyphenyl)thiomorpholin-5-one | CHE...) Show SMILES CCOc1ccc(cc1)C1CNC(=O)CS1 Show InChI InChI=1S/C12H15NO2S/c1-2-15-10-5-3-9(4-6-10)11-7-13-12(14)8-16-11/h3-6,11H,2,7-8H2,1H3,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Chile Curated by ChEMBL					Assay Description Inhibition of MAOB in rat brain mitochondrial suspension				Bioorg Med Chem 18: 1388-95 (2010) Article DOI: 10.1016/j.bmc.2010.01.029 BindingDB Entry DOI: 10.7270/Q2T72JD7
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50307371 ((+/-)-2-(4'-Ethoxyphenyl)thiomorpholin-5-one | CHE...) Show SMILES CCOc1ccc(cc1)C1CNC(=O)CS1 Show InChI InChI=1S/C12H15NO2S/c1-2-15-10-5-3-9(4-6-10)11-7-13-12(14)8-16-11/h3-6,11H,2,7-8H2,1H3,(H,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Chile Curated by ChEMBL					Assay Description Inhibition of MAOA in rat brain mitochondrial suspension				Bioorg Med Chem 18: 1388-95 (2010) Article DOI: 10.1016/j.bmc.2010.01.029 BindingDB Entry DOI: 10.7270/Q2T72JD7
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50307371 ((+/-)-2-(4'-Ethoxyphenyl)thiomorpholin-5-one | CHE...) Show SMILES CCOc1ccc(cc1)C1CNC(=O)CS1 Show InChI InChI=1S/C12H15NO2S/c1-2-15-10-5-3-9(4-6-10)11-7-13-12(14)8-16-11/h3-6,11H,2,7-8H2,1H3,(H,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Chile Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB by spectrophotometrically				Bioorg Med Chem 18: 1388-95 (2010) Article DOI: 10.1016/j.bmc.2010.01.029 BindingDB Entry DOI: 10.7270/Q2T72JD7
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50307371 ((+/-)-2-(4'-Ethoxyphenyl)thiomorpholin-5-one | CHE...) Show SMILES CCOc1ccc(cc1)C1CNC(=O)CS1 Show InChI InChI=1S/C12H15NO2S/c1-2-15-10-5-3-9(4-6-10)11-7-13-12(14)8-16-11/h3-6,11H,2,7-8H2,1H3,(H,13,14)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Chile Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA by spectrophotometrically				Bioorg Med Chem 18: 1388-95 (2010) Article DOI: 10.1016/j.bmc.2010.01.029 BindingDB Entry DOI: 10.7270/Q2T72JD7
					More data for this Ligand-Target Pair