BDBM50307451 3-[4-[(2,6-Difluorophenoxy)methyl]-2-({[1-(3,5-dimethylphenyl)-3-methylbutyl]amino}carbonyl)phenyl]propanoic acid::CHEMBL606197

SMILES: CC(C)CC(NC(=O)c1cc(COc2c(F)cccc2F)ccc1CCC(O)=O)c1cc(C)cc(C)c1

InChI Key: InChIKey=YQXPHUWJIAKOMU-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid EP3 Receptor (Mus musculus (Mouse))	BDBM50307451 (3-[4-[(2,6-Difluorophenoxy)methyl]-2-({[1-(3,5-dim...) Show SMILES CC(C)CC(NC(=O)c1cc(COc2c(F)cccc2F)ccc1CCC(O)=O)c1cc(C)cc(C)c1 Show InChI InChI=1S/C30H33F2NO4/c1-18(2)12-27(23-14-19(3)13-20(4)15-23)33-30(36)24-16-21(8-9-22(24)10-11-28(34)35)17-37-29-25(31)6-5-7-26(29)32/h5-9,13-16,18,27H,10-12,17H2,1-4H3,(H,33,36)(H,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membrane				Bioorg Med Chem 18: 1641-58 (2010) Article DOI: 10.1016/j.bmc.2009.12.068 BindingDB Entry DOI: 10.7270/Q29023W2
					More data for this Ligand-Target Pair
Prostanoid EP3 Receptor (Mus musculus (Mouse))	BDBM50307451 (3-[4-[(2,6-Difluorophenoxy)methyl]-2-({[1-(3,5-dim...) Show SMILES CC(C)CC(NC(=O)c1cc(COc2c(F)cccc2F)ccc1CCC(O)=O)c1cc(C)cc(C)c1 Show InChI InChI=1S/C30H33F2NO4/c1-18(2)12-27(23-14-19(3)13-20(4)15-23)33-30(36)24-16-21(8-9-22(24)10-11-28(34)35)17-37-29-25(31)6-5-7-26(29)32/h5-9,13-16,18,27H,10-12,17H2,1-4H3,(H,33,36)(H,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in prese...				Bioorg Med Chem 18: 1641-58 (2010) Article DOI: 10.1016/j.bmc.2009.12.068 BindingDB Entry DOI: 10.7270/Q29023W2
					More data for this Ligand-Target Pair