BDBM50307478 (1S,2R)-1-(6-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride::CHEMBL603920

SMILES: CNC[C@@H](O)[C@@H](N1CC(C)(C)c2ccc(F)cc12)c1cccc(F)c1

InChI Key: InChIKey=XNKYPTFOKMIDGF-MOPGFXCFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50307478 ((1S,2R)-1-(6-Fluoro-3,3-dimethyl-2,3-dihydro-1H-in...) Show SMILES CNC[C@@H](O)[C@@H](N1CC(C)(C)c2ccc(F)cc12)c1cccc(F)c1 |r| Show InChI InChI=1S/C20H24F2N2O/c1-20(2)12-24(17-10-15(22)7-8-16(17)20)19(18(25)11-23-3)13-5-4-6-14(21)9-13/h4-10,18-19,23,25H,11-12H2,1-3H3/t18-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR cells				J Med Chem 53: 2051-62 (2010) Article DOI: 10.1021/jm901559e BindingDB Entry DOI: 10.7270/Q21J99VS
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50307478 ((1S,2R)-1-(6-Fluoro-3,3-dimethyl-2,3-dihydro-1H-in...) Show SMILES CNC[C@@H](O)[C@@H](N1CC(C)(C)c2ccc(F)cc12)c1cccc(F)c1 |r| Show InChI InChI=1S/C20H24F2N2O/c1-20(2)12-24(17-10-15(22)7-8-16(17)20)19(18(25)11-23-3)13-5-4-6-14(21)9-13/h4-10,18-19,23,25H,11-12H2,1-3H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				J Med Chem 53: 2051-62 (2010) Article DOI: 10.1021/jm901559e BindingDB Entry DOI: 10.7270/Q21J99VS
					More data for this Ligand-Target Pair