BDBM50307782 7-(4-(3-Chloro-4-fluorophenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)-N-hydroxyheptanamide::CHEMBL597569

SMILES: COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCCCC(=O)NO

InChI Key: InChIKey=FEOPLVISXFSHGK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50307782 (7-(4-(3-Chloro-4-fluorophenylamino)-7-(2-methoxyet...) Show SMILES COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCCCC(=O)NO Show InChI InChI=1S/C24H28ClFN4O5/c1-33-10-11-35-22-14-20-17(13-21(22)34-9-5-3-2-4-6-23(31)30-32)24(28-15-27-20)29-16-7-8-19(26)18(25)12-16/h7-8,12-15,32H,2-6,9-11H2,1H3,(H,30,31)(H,27,28,29)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Curis Inc Curated by ChEMBL					Assay Description Inhibition of HER2				J Med Chem 53: 2000-9 (2010) Article DOI: 10.1021/jm901453q BindingDB Entry DOI: 10.7270/Q2CR5TGQ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50307782 (7-(4-(3-Chloro-4-fluorophenylamino)-7-(2-methoxyet...) Show SMILES COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCCCC(=O)NO Show InChI InChI=1S/C24H28ClFN4O5/c1-33-10-11-35-22-14-20-17(13-21(22)34-9-5-3-2-4-6-23(31)30-32)24(28-15-27-20)29-16-7-8-19(26)18(25)12-16/h7-8,12-15,32H,2-6,9-11H2,1H3,(H,30,31)(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Curis Inc Curated by ChEMBL					Assay Description Inhibition of EGFR				J Med Chem 53: 2000-9 (2010) Article DOI: 10.1021/jm901453q BindingDB Entry DOI: 10.7270/Q2CR5TGQ
					More data for this Ligand-Target Pair