BindingDB logo
myBDB logout

null

SMILES: Brc1cccc(Nc2ncnc3ccc(NC(=O)CNC(=O)Oc4ccccc4)cc23)c1

InChI Key: InChIKey=GKIQXUYTWFNMTA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307939   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50307939
PNG
(CHEMBL599863 | N-[2-[(4-(3-Bromoanilino)quinazolin...)
Show SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)CNC(=O)Oc4ccccc4)cc23)c1
Show InChI InChI=1S/C23H18BrN5O3/c24-15-5-4-6-16(11-15)29-22-19-12-17(9-10-20(19)26-14-27-22)28-21(30)13-25-23(31)32-18-7-2-1-3-8-18/h1-12,14H,13H2,(H,25,31)(H,28,30)(H,26,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.370n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorometry

J Med Chem 53: 2038-50 (2010)


Article DOI: 10.1021/jm901558p
BindingDB Entry DOI: 10.7270/Q2736R1N
More data for this
Ligand-Target Pair