BDBM50307972 4-(3-(Trifluoromethoxy)benzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-piperidin-4-amine::CHEMBL597818

SMILES: NC1(Cc2cccc(OC(F)(F)F)c2)CCN(CC1)c1ncnc2[nH]ccc12

InChI Key: InChIKey=FWXXBSHAGPYOEO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50307972 (4-(3-(Trifluoromethoxy)benzyl)-1-(7H-pyrrolo[2,3-d...) Show SMILES NC1(Cc2cccc(OC(F)(F)F)c2)CCN(CC1)c1ncnc2[nH]ccc12 Show InChI InChI=1S/C19H20F3N5O/c20-19(21,22)28-14-3-1-2-13(10-14)11-18(23)5-8-27(9-6-18)17-15-4-7-24-16(15)25-12-26-17/h1-4,7,10,12H,5-6,8-9,11,23H2,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of PKBbeta by radiometric filter binding assay				J Med Chem 53: 2239-49 (2010) Article DOI: 10.1021/jm901788j BindingDB Entry DOI: 10.7270/Q23B608V
					More data for this Ligand-Target Pair