BDBM50307977 4-(4-tert-Butylbenzyl)-1-(1H-pyrrolo[2,3-b]pyridin-4-yl)piperidin-4-amine::CHEMBL603262

SMILES: CC(C)(C)c1ccc(CC2(N)CCN(CC2)c2ccnc3[nH]ccc23)cc1

InChI Key: InChIKey=IYMBRDFKFRDOFJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM50307977 (4-(4-tert-Butylbenzyl)-1-(1H-pyrrolo[2,3-b]pyridin...) Show SMILES CC(C)(C)c1ccc(CC2(N)CCN(CC2)c2ccnc3[nH]ccc23)cc1 Show InChI InChI=1S/C23H30N4/c1-22(2,3)18-6-4-17(5-7-18)16-23(24)10-14-27(15-11-23)20-9-13-26-21-19(20)8-12-25-21/h4-9,12-13H,10-11,14-16,24H2,1-3H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of PKBbeta by radiometric filter binding assay				J Med Chem 53: 2239-49 (2010) Article DOI: 10.1021/jm901788j BindingDB Entry DOI: 10.7270/Q23B608V
					More data for this Ligand-Target Pair