BDBM50308005 1-(4-Fluorophenyl)-4-{[1-(4-fluorophenyl)-1H-pyrazol-4-yl]methyl}piperazine::CHEMBL598845

SMILES: Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccc(F)cc2)CC1

InChI Key: InChIKey=PUWHTHUIKFOAEI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50308005 (1-(4-Fluorophenyl)-4-{[1-(4-fluorophenyl)-1H-pyraz...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C20H20F2N4/c21-17-1-5-19(6-2-17)25-11-9-24(10-12-25)14-16-13-23-26(15-16)20-7-3-18(22)4-8-20/h1-8,13,15H,9-12,14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in Wistar rat hippocampus homogenate				Bioorg Med Chem 18: 1925-35 (2010) Article DOI: 10.1016/j.bmc.2010.01.040 BindingDB Entry DOI: 10.7270/Q2S75H99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50308005 (1-(4-Fluorophenyl)-4-{[1-(4-fluorophenyl)-1H-pyraz...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C20H20F2N4/c21-17-1-5-19(6-2-17)25-11-9-24(10-12-25)14-16-13-23-26(15-16)20-7-3-18(22)4-8-20/h1-8,13,15H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in Wistar rat cortex homogenate				Bioorg Med Chem 18: 1925-35 (2010) Article DOI: 10.1016/j.bmc.2010.01.040 BindingDB Entry DOI: 10.7270/Q2S75H99
					More data for this Ligand-Target Pair