BDBM50308017 2-Methyl-3-(4-phenylpiperazinylmethyl)imidazo[1,2-a]-pyridine::CHEMBL597006
SMILES: Cc1nc2ccccn2c1CN1CCN(CC1)c1ccccc1
InChI Key: InChIKey=TXCIWHWIDCDHAN-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50308017 (2-Methyl-3-(4-phenylpiperazinylmethyl)imidazo[1,2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Rio Grande do Sul Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in Wistar rat hippocampus homogenate | Bioorg Med Chem 18: 1925-35 (2010) Article DOI: 10.1016/j.bmc.2010.01.040 BindingDB Entry DOI: 10.7270/Q2S75H99 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50308017 (2-Methyl-3-(4-phenylpiperazinylmethyl)imidazo[1,2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Rio Grande do Sul Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in Wistar rat cortex homogenate | Bioorg Med Chem 18: 1925-35 (2010) Article DOI: 10.1016/j.bmc.2010.01.040 BindingDB Entry DOI: 10.7270/Q2S75H99 | |||||||||||
More data for this Ligand-Target Pair |