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BDBM50308258 1-O-Methyl-2,3-O-isopropylidene-5-(4-phenoxymethyl-1H-1,2,3-triazol-1-yl)-beta-D-ribofuranose::CHEMBL597996

SMILES: CO[C@@H]1O[C@H](Cn2cc(COc3ccccc3)nn2)[C@H]2OC(C)(C)O[C@@H]12

InChI Key: InChIKey=ZSKICKWULFPVRO-QBPKDAKJSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308258   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-glucosidase MAL12


(Saccharomyces cerevisiae)		BDBM50308258
PNG
(1-O-Methyl-2,3-O-isopropylidene-5-(4-phenoxymethyl...)
Show SMILES CO[C@@H]1O[C@H](Cn2cc(COc3ccccc3)nn2)[C@H]2OC(C)(C)O[C@@H]12 |r|
Show InChI InChI=1S/C18H23N3O5/c1-18(2)25-15-14(24-17(22-3)16(15)26-18)10-21-9-12(19-20-21)11-23-13-7-5-4-6-8-13/h4-9,14-17H,10-11H2,1-3H3/t14-,15-,16-,17-/m1/s1
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Article
PubMed
n/an/a 5.70E+3n/an/an/an/an/an/a



Universidade Federal do Rio de Janeiro

Curated by ChEMBL


Assay Description
Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometry

J Med Chem 53: 2364-75 (2010)


Article DOI: 10.1021/jm901265h
BindingDB Entry DOI: 10.7270/Q20R9QC7
More data for this
Ligand-Target Pair