BDBM50308754 3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimethoxybenz[f]indazol-4,9-dione::CHEMBL591062

SMILES: COC(=O)NCCc1n[nH]c2c1C(=O)c1c(OC)c(Cl)c(Cl)c(OC)c1C2=O

InChI Key: InChIKey=JPZQPQKEEWNUEC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308754 (3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimet...) Show SMILES COC(=O)NCCc1n[nH]c2c1C(=O)c1c(OC)c(Cl)c(Cl)c(OC)c1C2=O Show InChI InChI=1S/C17H15Cl2N3O6/c1-26-15-8-9(16(27-2)11(19)10(15)18)14(24)12-7(13(8)23)6(21-22-12)4-5-20-17(25)28-3/h4-5H2,1-3H3,(H,20,25)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308754 (3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimet...) Show SMILES COC(=O)NCCc1n[nH]c2c1C(=O)c1c(OC)c(Cl)c(Cl)c(OC)c1C2=O Show InChI InChI=1S/C17H15Cl2N3O6/c1-26-15-8-9(16(27-2)11(19)10(15)18)14(24)12-7(13(8)23)6(21-22-12)4-5-20-17(25)28-3/h4-5H2,1-3H3,(H,20,25)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
					More data for this Ligand-Target Pair