null

SMILES: CN(C)Cc1ccc(NC(=O)c2cccc(CNC(=O)c3ccc(cc3)C#N)c2)cc1

InChI Key: InChIKey=RXEBZMMATZDNTI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50308863 (4-Cyano-N-[3-(4-dimethylaminomethyl-phenylcarbamoy...) Show SMILES CN(C)Cc1ccc(NC(=O)c2cccc(CNC(=O)c3ccc(cc3)C#N)c2)cc1 Show InChI InChI=1S/C25H24N4O2/c1-29(2)17-19-8-12-23(13-9-19)28-25(31)22-5-3-4-20(14-22)16-27-24(30)21-10-6-18(15-26)7-11-21/h3-14H,16-17H2,1-2H3,(H,27,30)(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ROCK2 by IMAP assay				J Med Chem 53: 759-77 (2010) Article DOI: 10.1021/jm9014263 BindingDB Entry DOI: 10.7270/Q2V125RD
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50308863 (4-Cyano-N-[3-(4-dimethylaminomethyl-phenylcarbamoy...) Show SMILES CN(C)Cc1ccc(NC(=O)c2cccc(CNC(=O)c3ccc(cc3)C#N)c2)cc1 Show InChI InChI=1S/C25H24N4O2/c1-29(2)17-19-8-12-23(13-9-19)28-25(31)22-5-3-4-20(14-22)16-27-24(30)21-10-6-18(15-26)7-11-21/h3-14H,16-17H2,1-2H3,(H,27,30)(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.70E+6	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ROCK2 by homogenous luciferase assay				J Med Chem 53: 759-77 (2010) Article DOI: 10.1021/jm9014263 BindingDB Entry DOI: 10.7270/Q2V125RD
					More data for this Ligand-Target Pair