BDBM50308889 4-Methoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)-benzyl]-benzamide::CHEMBL596708

SMILES: COc1ccc(cc1)C(=O)NCc1cccc(c1)C(=O)NCCc1ccncc1

InChI Key: InChIKey=WWPWTEOCRKWNBN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50308889 (4-Methoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)-ben...) Show SMILES COc1ccc(cc1)C(=O)NCc1cccc(c1)C(=O)NCCc1ccncc1 Show InChI InChI=1S/C23H23N3O3/c1-29-21-7-5-19(6-8-21)22(27)26-16-18-3-2-4-20(15-18)23(28)25-14-11-17-9-12-24-13-10-17/h2-10,12-13,15H,11,14,16H2,1H3,(H,25,28)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ROCK2 by IMAP assay				J Med Chem 53: 759-77 (2010) Article DOI: 10.1021/jm9014263 BindingDB Entry DOI: 10.7270/Q2V125RD
					More data for this Ligand-Target Pair