BDBM50309053 CHEMBL600242::trans-2-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-5-(3,4-difluorobenzyl)piperidine

SMILES: Fc1ccc(C[C@H]2CC[C@@H](N(C2)c2ccc(Cl)cc2Cl)c2ccc(Cl)cc2)cc1F

InChI Key: InChIKey=WGKCYRNWFRCSGK-WAIKUNEKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50309053 (CHEMBL600242 | trans-2-(4-chlorophenyl)-1-(2,4-dic...) Show SMILES Fc1ccc(C[C@H]2CC[C@@H](N(C2)c2ccc(Cl)cc2Cl)c2ccc(Cl)cc2)cc1F |r| Show InChI InChI=1S/C24H20Cl3F2N/c25-18-5-3-17(4-6-18)23-9-2-16(11-15-1-8-21(28)22(29)12-15)14-30(23)24-10-7-19(26)13-20(24)27/h1,3-8,10,12-13,16,23H,2,9,11,14H2/t16-,23-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	467	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human CB1 receptor				Bioorg Med Chem Lett 20: 1278-83 (2010) Article DOI: 10.1016/j.bmcl.2009.11.075 BindingDB Entry DOI: 10.7270/Q2B27W7Z
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50309053 (CHEMBL600242 | trans-2-(4-chlorophenyl)-1-(2,4-dic...) Show SMILES Fc1ccc(C[C@H]2CC[C@@H](N(C2)c2ccc(Cl)cc2Cl)c2ccc(Cl)cc2)cc1F |r| Show InChI InChI=1S/C24H20Cl3F2N/c25-18-5-3-17(4-6-18)23-9-2-16(11-15-1-8-21(28)22(29)12-15)14-30(23)24-10-7-19(26)13-20(24)27/h1,3-8,10,12-13,16,23H,2,9,11,14H2/t16-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human CB2 receptor				Bioorg Med Chem Lett 20: 1278-83 (2010) Article DOI: 10.1016/j.bmcl.2009.11.075 BindingDB Entry DOI: 10.7270/Q2B27W7Z
					More data for this Ligand-Target Pair