BDBM50309136 (2R,3R)-2,3-dihydroxy-N1,N1-dimethyl-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL597340

SMILES: CN(C)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1

InChI Key: InChIKey=KTPYHCDQOGGTRF-NXEZZACHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50309136 ((2R,3R)-2,3-dihydroxy-N1,N1-dimethyl-N4-(2-(thioph...) Show SMILES CN(C)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 |r| Show InChI InChI=1S/C12H18N2O4S/c1-14(2)12(18)10(16)9(15)11(17)13-6-5-8-4-3-7-19-8/h3-4,7,9-10,15-16H,5-6H2,1-2H3,(H,13,17)/t9-,10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Cambridge Curated by ChEMBL					Assay Description Inhibition of TACE				Bioorg Med Chem Lett 20: 1189-93 (2010) Article DOI: 10.1016/j.bmcl.2009.12.004 BindingDB Entry DOI: 10.7270/Q2BK1CFB
					More data for this Ligand-Target Pair