BDBM50309143 (2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpiperidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL592722

SMILES: O[C@H]([C@@H](O)C(=O)N1CCCCC1c1ccccc1)C(=O)NCCc1cccs1

InChI Key: InChIKey=CJECZLMWLDBDOZ-OMKBGSMGSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50309143 ((2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpiperidin-1...) Show SMILES O[C@H]([C@@H](O)C(=O)N1CCCCC1c1ccccc1)C(=O)NCCc1cccs1 |r| Show InChI InChI=1S/C21H26N2O4S/c24-18(20(26)22-12-11-16-9-6-14-28-16)19(25)21(27)23-13-5-4-10-17(23)15-7-2-1-3-8-15/h1-3,6-9,14,17-19,24-25H,4-5,10-13H2,(H,22,26)/t17?,18-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	325	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Cambridge Curated by ChEMBL					Assay Description Inhibition of TACE				Bioorg Med Chem Lett 20: 1189-93 (2010) Article DOI: 10.1016/j.bmcl.2009.12.004 BindingDB Entry DOI: 10.7270/Q2BK1CFB
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