BDBM50309295 2-(2-(bis(4-methoxyphenyl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid::CHEMBL606389

SMILES: COc1ccc(cc1)C(c1nc(c(CC(O)=O)s1)-c1ccc(F)cc1)c1ccc(OC)cc1

InChI Key: InChIKey=ZOTGQGLOXKIJDG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309295 (2-(2-(bis(4-methoxyphenyl)methyl)-4-(4-fluoropheny...) Show SMILES COc1ccc(cc1)C(c1nc(c(CC(O)=O)s1)-c1ccc(F)cc1)c1ccc(OC)cc1 Show InChI InChI=1S/C26H22FNO4S/c1-31-20-11-5-16(6-12-20)24(17-7-13-21(32-2)14-8-17)26-28-25(22(33-26)15-23(29)30)18-3-9-19(27)10-4-18/h3-14,24H,15H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of[3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cells				Bioorg Med Chem Lett 20: 1181-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.015 BindingDB Entry DOI: 10.7270/Q2PR7W35
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309295 (2-(2-(bis(4-methoxyphenyl)methyl)-4-(4-fluoropheny...) Show SMILES COc1ccc(cc1)C(c1nc(c(CC(O)=O)s1)-c1ccc(F)cc1)c1ccc(OC)cc1 Show InChI InChI=1S/C26H22FNO4S/c1-31-20-11-5-16(6-12-20)24(17-7-13-21(32-2)14-8-17)26-28-25(22(33-26)15-23(29)30)18-3-9-19(27)10-4-18/h3-14,24H,15H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...				Bioorg Med Chem Lett 20: 1181-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.015 BindingDB Entry DOI: 10.7270/Q2PR7W35
					More data for this Ligand-Target Pair