null

SMILES: Clc1cccc2N3CCNCC3NC(=O)c12

InChI Key: InChIKey=HVGOEFOHXQIZBF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50309338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50309338 (7-chloro-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...) Show SMILES Clc1cccc2N3CCNCC3NC(=O)c12 Show InChI InChI=1S/C11H12ClN3O/c12-7-2-1-3-8-10(7)11(16)14-9-6-13-4-5-15(8)9/h1-3,9,13H,4-6H2,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Displacement of [125I]LSD from human recombinant 5HT2B receptor expressed in HEK293E cells				Bioorg Med Chem Lett 20: 1128-33 (2010) Article DOI: 10.1016/j.bmcl.2009.12.014 BindingDB Entry DOI: 10.7270/Q2K074DK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50309338 (7-chloro-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...) Show SMILES Clc1cccc2N3CCNCC3NC(=O)c12 Show InChI InChI=1S/C11H12ClN3O/c12-7-2-1-3-8-10(7)11(16)14-9-6-13-4-5-15(8)9/h1-3,9,13H,4-6H2,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293E cells				Bioorg Med Chem Lett 20: 1128-33 (2010) Article DOI: 10.1016/j.bmcl.2009.12.014 BindingDB Entry DOI: 10.7270/Q2K074DK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50309338 (7-chloro-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...) Show SMILES Clc1cccc2N3CCNCC3NC(=O)c12 Show InChI InChI=1S/C11H12ClN3O/c12-7-2-1-3-8-10(7)11(16)14-9-6-13-4-5-15(8)9/h1-3,9,13H,4-6H2,(H,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	334	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293E cells				Bioorg Med Chem Lett 20: 1128-33 (2010) Article DOI: 10.1016/j.bmcl.2009.12.014 BindingDB Entry DOI: 10.7270/Q2K074DK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50309338 (7-chloro-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...) Show SMILES Clc1cccc2N3CCNCC3NC(=O)c12 Show InChI InChI=1S/C11H12ClN3O/c12-7-2-1-3-8-10(7)11(16)14-9-6-13-4-5-15(8)9/h1-3,9,13H,4-6H2,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor expressed in HEK293E cells by FLIPR assay				Bioorg Med Chem Lett 20: 1128-33 (2010) Article DOI: 10.1016/j.bmcl.2009.12.014 BindingDB Entry DOI: 10.7270/Q2K074DK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50309338 (7-chloro-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...) Show SMILES Clc1cccc2N3CCNCC3NC(=O)c12 Show InChI InChI=1S/C11H12ClN3O/c12-7-2-1-3-8-10(7)11(16)14-9-6-13-4-5-15(8)9/h1-3,9,13H,4-6H2,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in HEK293E cells by FLIPR assay				Bioorg Med Chem Lett 20: 1128-33 (2010) Article DOI: 10.1016/j.bmcl.2009.12.014 BindingDB Entry DOI: 10.7270/Q2K074DK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50309338 (7-chloro-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...) Show SMILES Clc1cccc2N3CCNCC3NC(=O)c12 Show InChI InChI=1S/C11H12ClN3O/c12-7-2-1-3-8-10(7)11(16)14-9-6-13-4-5-15(8)9/h1-3,9,13H,4-6H2,(H,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2A receptor expressed in HEK293E cells by FLIPR assay				Bioorg Med Chem Lett 20: 1128-33 (2010) Article DOI: 10.1016/j.bmcl.2009.12.014 BindingDB Entry DOI: 10.7270/Q2K074DK
					More data for this Ligand-Target Pair