Found 2 hits for monomerid = 50309497 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50309497
((2S,3S,11bS)-9,10-dimethoxy-3-(4-methylpyridin-2-y...)Show SMILES COc1cc2CCN3C[C@@H]([C@@H](N)C[C@H]3c2cc1OC)c1cc(C)ccn1 |r| Show InChI InChI=1S/C21H27N3O2/c1-13-4-6-23-18(8-13)16-12-24-7-5-14-9-20(25-2)21(26-3)10-15(14)19(24)11-17(16)22/h4,6,8-10,16-17,19H,5,7,11-12,22H2,1-3H3/t16-,17-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
F Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 20: 1106-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.025 BindingDB Entry DOI: 10.7270/Q2SJ1KQ3 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50309497
((2S,3S,11bS)-9,10-dimethoxy-3-(4-methylpyridin-2-y...)Show SMILES COc1cc2CCN3C[C@@H]([C@@H](N)C[C@H]3c2cc1OC)c1cc(C)ccn1 |r| Show InChI InChI=1S/C21H27N3O2/c1-13-4-6-23-18(8-13)16-12-24-7-5-14-9-20(25-2)21(26-3)10-15(14)19(24)11-17(16)22/h4,6,8-10,16-17,19H,5,7,11-12,22H2,1-3H3/t16-,17-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
F Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 20: 1106-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.025 BindingDB Entry DOI: 10.7270/Q2SJ1KQ3 |
More data for this Ligand-Target Pair | |