BDBM50309876 4-(6-Ethyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]-nonane::CHEMBL597441

SMILES: CCc1cnc2nc(oc2c1)N1CCN2CCC1CC2

InChI Key: InChIKey=PSCRTYZAAGWMLR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50309876 (4-(6-Ethyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...) Show SMILES CCc1cnc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:7:11:16.15:18.19,(30.33,-18.3,;28.77,-18.33,;28.02,-19.69,;28.99,-20.9,;28.43,-22.34,;26.9,-22.57,;26.05,-23.85,;24.56,-23.44,;24.5,-21.91,;25.94,-21.36,;26.49,-19.93,;23.23,-24.22,;23.59,-25.68,;22.59,-24.96,;21.21,-25.03,;21.14,-23.33,;21.76,-22.18,;21.82,-23.6,;20.52,-24.3,;20.22,-25.74,)| Show InChI InChI=1S/C15H20N4O/c1-2-11-9-13-14(16-10-11)17-15(20-13)19-8-7-18-5-3-12(19)4-6-18/h9-10,12H,2-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM50309876 (4-(6-Ethyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...) Show SMILES CCc1cnc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:7:11:16.15:18.19,(30.33,-18.3,;28.77,-18.33,;28.02,-19.69,;28.99,-20.9,;28.43,-22.34,;26.9,-22.57,;26.05,-23.85,;24.56,-23.44,;24.5,-21.91,;25.94,-21.36,;26.49,-19.93,;23.23,-24.22,;23.59,-25.68,;22.59,-24.96,;21.21,-25.03,;21.14,-23.33,;21.76,-22.18,;21.82,-23.6,;20.52,-24.3,;20.22,-25.74,)| Show InChI InChI=1S/C15H20N4O/c1-2-11-9-13-14(16-10-11)17-15(20-13)19-8-7-18-5-3-12(19)4-6-18/h9-10,12H,2-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair